Dermatology for PM Artists: Tattoo-Associated Reactions

Complications in permanent makeup

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The reaction of the skin to the introduction of the pigment may be unexpected, and not a single PM master is immune from this. We propose to consider the most common complications caused by dyes used in permanent makeup.

Tatyana Svyatenko, State Institution "DMA of the Ministry of Health of Ukraine", Center for Dermatology and Cosmetology of Professor Svyatenko (Ukraine)

Dinara Sagnaeva, JSC "Astana Medical University" (Kazakhstan)

Evgeny Vasilchuk, TMO "Dermatovenereology" (Ukraine)

The relevance of writing this article was dictated by the increase in the number of people using tattoos for cosmetic purposes, such as permanent makeup of lips, eyes, eyebrows. As well as the lack of a management system for the tattooing procedure and certification of products for permanent makeup and an increase in the frequency of tattoo-associated medical complications.

The most common tattoo-associated dermatological complications can be classified as follows: allergic, bacterial, viral, neoplastic, exacerbation of existing dermatoses ( Koebner phenomenon ).

Patient, 37 years old, granulation cysts after lip tattooing.

The patient, 29 years old, has a history of psoriasis, the occurrence of Koebner's symptom at the site of the tattoo

Currently, it is customary to use the following tactics for managing patients:

  • topical glucocorticosteroids (including intralesional administration and phonophoretic administration);
  • laser therapy (use of various lasers).

Our observations

A 52-year-old patient addressed a dermatologist with complaints that 2–3 months after the tattooing procedure, persistent swelling appeared in the area of pigment injection, redness, and intense itching (photo 1-2). The patient was prescribed therapy: antihistamines - no effect, topical superstrong steroids - no effect.

Photo 1. Clinical picture before treatment.

Photo 2. Dermoscopic picture before treatment.

In order to conduct a differential diagnosis, the patient underwent a punch biopsy followed by a histological examination.

Result: the morphological picture corresponds to sarcoidosis that developed at the site of the tattoo. As is known, standard dermatological treatment includes the use of systemic corticosteroids in low doses or intralesional corticosteroids.

The patient was also prescribed the following alternative treatment: laser ablation (Er:Yag laser, ultrashort pulse 350–400 J). After the treatment, a positive clinical and aesthetic result was obtained (photo 3-4).

Photo 3. Clinical picture after treatment.

Photo 4. Dermoscopic picture after treatment.

Thus, the described cases testify to the importance of sufficient professional training in the section " tattoo-associated reactions " for all professionals practicing in the field of tattooing.

It must be remembered that timely prevention of complications consists, first of all, in a careful history taking, prescribing, if necessary, prophylactic doses of antiviral drugs, an adequate rehabilitation period, the use of sunscreens, and disposable instruments.

Training and education can significantly reduce the number of complications that occur.

Classification of used dyes
Color Dye
Red Mercury sulfide (cinnabar), cadmium selenide, iron hydrate, sandalwood, brazilwood, aromatic azo compounds including naphthol-AS, quinacridone
Green Chromium oxide, lead chromate, copper or aluminum phthalocyanine, malachite (contains copper), ferrocyanides
Violet Manganese ammonium periphosphate, aluminum salts, quinacridone, diaxazine/carbazole
Blue Cobalt oxide, chromium oxide, copper phthalocyanine
Yellow Cadmium sulfide, turmeric, chromium yellow (mixture of lead chromate and lead sulfide)
Black Indian ink
Brown iron oxide
Types of complications caused by dyes
Dye components Complications
Red pigment containing mercury Contact allergic dermatitis, lichenoid reaction
Yellow photoinduced allergic reaction
Red pigment containing mercury; green pigment containing chromium; blue pigment containing cobalt; purple pigment containing manganese Granulomatous reaction
Red pigment containing mercury; green pigment containing chromium; blue pigment containing cobalt Pseudolymphomatous reaction
Violet pigment containing manganese Granulomatous reaction
Laser therapy
Type of laser Wavelength Pulse duration Flow J/cm2 Target (tattoo color)
Nd:YAG 1084 10 6-12 Black, blue
Nd:YAG double frequency 532 10 2-12 Red, orange, purple
Ruby 694 25 8-10 Black, blue, green
alexandrite 755 50-100 4.5-8 Black, blue, green

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