Anti-aging procedures: what to consider when prescribing

The intercellular lipid matrix is ​​formed in the granular layer of the epidermis and provides a protective function for the skin. The main moisture loss occurs through the intercellular hydrophilic channels of the lipid matrix. The alternation of hydrophilic and lipid layers of the intercellular matrix keeps transepidermal water loss (TEWL) at a constant level.

There is evidence that with aging, the level of transepidermal moisture loss not only does not increase, but also tends to decrease. However, when the epidermal barrier is disrupted, the restoration of moisture-retaining function slows down, which must be remembered when performing procedures related to chemical and physical damage to the skin.

The water content in the stratum corneum largely depends on its moisture-retaining capacity and the condition of the skin's hydrolipidic mantle. Dry skin is more prone to wrinkles and is more sensitive to aggressive environmental factors.

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