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Solutions for skin pigmentation: what works and what doesn't

Mechanism of pigmentation disorders: what happens in the skin?

2025-04-04
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What is melanin and why do we need it?

Melanin is a natural pigment produced by special cells called melanocytes in the skin. It determines the color of the skin, hair, and eyes, but its main function is protective. Melanin protects skin cells and their DNA from mutations and damage, including from free radicals and ultraviolet radiation.

Melanin works like a “solar panel” in the skin, but instead of generating energy, it does the opposite: it absorbs ultraviolet light and converts it into safe heat that is radiated by the surface layers of the skin. It also neutralizes free radicals, converting them into less active compounds that do not harm cells.

When melanin production is reduced or levels drop, the skin becomes more vulnerable to UV rays and air pollution. This leads to increased sensitivity, irritation, impaired barrier function, dryness, and chronic inflammation. In other words, melanin is vital for skin health.

Full version of the access article in Ukrainian

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