Hormone-dependent skin aging: estrogen levels and involution processes

2025-11-17

Healthy longevity is the slogan of the 21st century. The increase in aesthetic requirements for the appearance of a mature person, observed in recent years, is partly dictated by the increase in social activity of people of mature age. At one time, the strict Coco Chanel said that at 20 years old a woman looks the way God created her, at 30 - the way she wants it, at 50 - the way she deserves it. Unfortunately, Coco did not tell us how to deserve a beautiful old age. Let's try to fill this gap.

Aging is a permanent process – the first wrinkles appear as early as the age of twenty. And the explanation of this process cannot be reduced to the action of any one factor. Today, there are a number of theories of aging (the theory of reproductive system involution, free radical theory, the theory of platelet-endothelial interaction disorders, etc.), and each of them allows you to develop specific programs of cosmetic and anti-age measures to correct age-related skin changes. Clearly noticeable age-related changes are explained by the theory of “wear and tear” and endocrine aging. According to it, with age, the amount of hormones produced decreases, which affects the body’s ability to self-regulate.

Hormonal aging is based on the age-related extinction of the body’s reproductive function. This is manifested in a decrease in the production of sex steroids by the testicles in men and complete suppression of ovarian function in women. Therefore, in order to maintain the previous metabolism and slow down the age-related signs of wear and tear of the body, it is necessary to support, and later stimulate the production of hormones.

The process of skin withering goes through several involutive stages.

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