Therapy and methods of hyperpigmentation correction

The expressiveness and activity of pigmentation in the skin depends on many factors:

1. Genetic predisposition. The number of melanocytes, the type of synthesized melanin (eumelanin or pheomelanin), as well as the uniformity of pigment distribution are genetically determined and determine the individual phototype of human skin.
2. Hormonal status. Thyroxine and thyronine, ACTH, estrogens, melanostimulating hormone are most important for melanogenesis.
3. The intensity of ultraviolet radiation. Infrared and X-ray radiation can also initiate pigmentation.
4. Mediator of inflammation. UV-irradiated keratinocytes secrete mainly interleukin-1, endothelin-1 and granulocyte-macrophage-colony-stimulating factor. These cytokines at a concentration of 1-100 nm stimulate DNA synthesis in melanocyte culture.
5. The use of photosensitizers is also often the main cause of hyperpigmentation. Vitamins and trace elements.
6. Vitamins B1, B2, C, pantothenic acid, copper, iron, zinc play an important role in the synthesis of melanin.

Laboratoires Renophase is a French cosmeceutical brand that has established itself as a leader in the field of skin restoration and rejuvenation. The basis of the product's action is the control of biological skin processes and cell regeneration. Step-by-step work with the skin, where each stage corresponds to its own cosmetic products and methods of achieving the desired effect. More than 35 years of success in the world market of dermatocosmetology have provided Renophase laboratories with a large evidence base for the effectiveness of drugs.

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This article is part of the special project Skin pigmentation and its correction

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