Systemic retinoids: aspects of application in medical and cosmetic practice

Retinoids are any agents that can induce specific biological responses by binding to and activating retinoic acid receptors. Retinoids are a class of compounds chemically related to retinol, its biological forms, and structural synthetic derivatives that differ significantly from the isoprene structure of natural vitamin A, but act in a similar way - through the activation of nuclear retinoic receptors, they regulate the processes of proliferation, differentiation, and intercellular communication of cells. Within the retinoid group itself, there is significant heterogeneity in both properties and results of clinical use.

Proven efficacy

Today, retinoids are one of the most effective groups of drugs. Their use in practice has become a turning point in the therapy of some dermatoses. In recent years, dermatocosmetologists have become more likely to use both topical and systemic retinoids in the treatment of acne patients. This is due to the experience of their use in real clinical practice in Ukraine, as well as the confidence of specialists in the high safety of systemic retinoids during long-term use in people with severe acne.

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