A comprehensive approach to solving aesthetic skin problems: the use of pharmacological agents

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Hormonal therapy

Medicines containing hormones are prescribed only to women with late hyperandrogenic, persistent acne, menstrual cycle disorders and other signs of hyperandrogenism, in the absence of the effect of standard antibiotic treatment. Local therapy should be prescribed along with hormone treatment.

Currently, progestagen and combined estrogen-progestagen contraceptives are used as antiandrogen drugs, the antiandrogen effect of which is based on the principle of competitive binding of receptors in target organs, including sebaceous glands, as well as a direct effect on comedogenesis.

In combined estrogen-progestogen preparations, the estrogen component is ethinyl estradiol, and the progestogen component is various synthetic progestogens. As you know, many metabolic effects of estrogens and progestogens are multidirectional, but mutually influence each other's metabolism.

When taking hormonal drugs, the development of complications is possible - secondary amenorrhea caused by ovarian hyperinhibition syndrome, risk of blood clots, tendency to hypertension, impaired glucose tolerance. These disorders have a pronounced dose-dependent effect.

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