Vitiligo
*The article was translated into English using automatic translation. The editors are working on its improvement.
Vitiligo (lat. vitiligo - “skin disease”, from vitium - “defect”) is a chronic disease of unknown etiology, characterized by pigmentation disorders and the appearance of depigmented spots and bleached hair on various parts of the body due to the destruction and decrease in the number of melanocytes in the skin.
The etiology of vitiligo is not clear. There are several hypotheses for the pathogenesis of the disease, including genetic, autoimmune, neurohumoral, etc. According to most experts, the leading role in damage to melanocytes and disruption of melanogenesis processes in the skin of patients with vitiligo is given to autoimmune mechanisms.
Occurs on the skin, presumably as a result of the action of certain medicinal and chemical substances, neurotrophic, neuroendocrine and autoimmune factors of melanogenesis, as well as after inflammatory and necrotic processes on the skin. A predisposition to vitiligo can be inherited.