Anaphylactic shock
*The article was translated into English using automatic translation. The editors are working on its improvement.
Anaphylactic shock , anaphylaxis (Latin shock anaphylacticum ; English anaphylactic shock ) is one of the types of shock, an emergency condition that occurs upon repeated contact with an allergen to which the body is sensitized (increased sensitivity of the immune system).
As a result of immediate reactions with the formation of “allergen-antibody” complexes, a cascade of severe hemodynamic disorders is triggered (increased permeability of blood vessels, disruption of the central nervous system (CNS), airway obstruction, smooth muscle spasm), leading to severe tissue hypoxia. The condition is potentially life-threatening, since the pressure drops sharply, body tissues are deprived of the nutrition and oxygen they need, which requires first aid and subsequent resuscitation by medical personnel.
The rate of occurrence of anaphylactic shock ranges from a few seconds or minutes to 1.5 hours from the start of contact with the allergen. In the development of an anaphylactic reaction in patients with a high degree of sensitization, neither the dose nor the method of administration of the allergen plays a decisive role. However, a large dose of the drug increases the severity and duration of shock.