Forgot your password?

Registration

company

brands

An unpredictable error occurred on the server. It will be fixed soon

Did you notice an error? Contact the editor

A confirmation email has been sent to your {email} email!

Your password has been successfully changed!

Something went wrong. Please try again later.

The password change request has been successfully sent to your email address.

Rules for publishing comments

The article was translated into English using automatic translation. The editors are working on its improvement.

we are working on a translation. Follow the link or use Google Translate

Skin quality

Science

Vitamin B1 (thiamine) was the first vitamin isolated from rice bran in crystalline form by K. Funk in 1912 (according to other data, it was first isolated by U. Suzuki in 1910). It is called thiamine because it contains sulfur (Greek - &quot;thion&quot;) and an amino group.

Metabolism. Thiamine, received with food, is absorbed into the blood in the small intestine by simple diffusion. In the liver, a large part of thiamine is phosphorylated by the enzyme thiamine phosphokinase to thiamine monophosphate (TMF), thiamine diphosphate (TDP) and thiamine triphosphate (TTP). Thiamine then undergoes biotransformation, and the resulting conjugates are excreted in the urine. Certain amounts of thiamine are deposited in tissues. It should be taken into account that thiamine is destroyed at increased alkalinity of the environment.

Biochemical functions. Thiamin diphosphate is a coenzyme of decarboxylases involved in the oxidative decarboxylation of keto acids (pyruvic, &alpha;-ketoglutaric), as well as transketolase in the pentose phosphate pathway of glucose breakdown. Therefore, with a lack of thiamine, carbohydrate metabolism is sharply disrupted, and then other types of metabolism. Pyruvic and lactic acids accumulate in the blood and tissues.

Full version of the access article <a href="https://pro.bhub.com.ua/cosmetology/vodorozchinni-vitamini-znachennya-dlya-zdorovya-ta-krasi">in Ukrainian</a>

Water-soluble vitamins: importance for health and beauty