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Therapy

<a href="https://special.bhub.com.ua/acne2-0" style="text-align: center; font-size: 16px;" target="_blank"><img alt="" src="https://pro.bhub.com.ua/cosmetology/upload/files/%D0%A1%D0%90%D0%99%D0%A2/123/1/1/BANER_ACNE-light.gif" style="width: 1200px; height: 200px;" /></a> “... Waking up in the morning, first I go to the mirror and see again three new pimples on my face. My morning started again with a high dose of cortisol and a bad mood. I quickly squeezed them out, wiped the blood dripping from my cheek, and applied a cotton pad soaked in calendula tincture. On the way to the university, I met the gazes of those around me, intently looking at my blue face after cleansing, took out a scarf, wrapped it around me and, lowering my head, moved on...” This is what I heard from one of my patients. What could this mean? The fact that this disease affects the psycho-emotional state leads to asociality and complexness. Acne is one of the most common dermatological diseases that occurs in our daily practice [1]. This disease affects approximately 85% of people aged 12-24 years [2, 3]. As a rule, acne occurs in patients during puberty, when, with an increase in the level of androgens, the sebaceous glands are activated, their hypertrophy occurs and, as a result, hyperproduction of sebum (sebum). It is considered a strong pro-inflammatory factor, providing the release of inflammatory mediators, which is associated with the development of severe forms of acne [4, 5]. Normalization of sebum production is a key point in prevention and treatment. The main factors for the development <a href="https://pro.bhub.com.ua/cosmetology/beautypedia/akne" target="_blank">of acne</a> include the following: 1) Heredity – size, number, activity of the sebaceous gland and its sensitivity to sex hormones [6]. 2) Impaired keratinization, when corneocytes do not exfoliate from the surface of the epithelium and, when accumulated, close the mouth of the excretory duct, creating optimal conditions for Propionibacterium acnes [7]. 3) Hormonal factors: PCOS (polycystic ovary syndrome) and other diseases associated with hyperandrogenism [8]. By adhering to the treatment protocol and having a wide range of cosmetic procedures, we can speed up the regeneration process and, most importantly, reduce the signs of post-acne. One of the main methods is the use of autologous platelet-rich plasma [9, 10]. Plasma therapy is a method of regenerative medicine that restores the integrity and function of tissue and cellular structures using autologous growth factors [10]. What is important for us when conducting plasma therapy? - Bactericidal and bacteriostatic properties [11]. - Stimulation of local immunity [10, 12]. - Lack of leukocytes [13, 14, 15]. Clinical case analysis Patient V. (born in 2001) Diagnosis: acne vulgaris, papulopustular form, moderate severity. In photo 1 we see the clinical picture of a patient with multiple papulopustular rashes on the face, stagnant spots, post-acne scars. From the anamnesis we find out that this disease bothered the patient for 5 years, the rashes were localized on the back and chest. He was treated with systemic antibiotics (azithromycin 250 mg per day for 8 weeks, after completing the course he was switched to systemic retinoids (acnetin) 16 mg per day for 2.5 months. Diagnostics. The following tests were ordered: CBC (complete blood count). BAC (biochemical blood test) ALT, AST, total protein, bilirubin, cholesterol. Glucose, insulin, ferritin. Vitamin D Analysis for Helicobacter pylori. Cortisol. Ultrasound – OBP, thyroid gland. Based on the test results, the following treatment was prescribed: 1) Enterosgel – 1 s/l 2 times a day 1 hour before or after meals, 7 days. 2) Enterol – 1 capsule 2 times a day, 14 days. 3) Dermapro – 1 capsule 2 times a day, 30 days. 4) Omega 3-6 – 2000 mg per day with meals, 6 months. 5) Decrystol – 2000 mg per day with meals, 4 months. 6) Zinc picolinate (Solgar) – 1 tablet 2 times a day with meals, 3 months. In the fourth month of treatment, the drug roacutane 10 mg per day for 6 months was prescribed to reduce sebum secretion and prevent relapse (photo 2 A-B). During systemic treatment, the patient also underwent: 1) four procedures of 25% salicylic peeling, 1 procedure every 10 days with a gradual increase in the number of layers applied; 2) plasma therapy Endoret, one procedure every 3 weeks, 4 procedures. Home Recommendations: - limiting the consumption of dairy products and simple carbohydrates; - maintaining healthy sleep from 23:00 to 07:00 to control cortisol levels; - use of DMK cosmeceuticals; - benzoyl peroxide 5%, topical retinoid Revitosin in the evening; - benzoyl peroxide 5%, Acu moist, Herb mineral spray in the morning. Adhering to this treatment regimen, we got a good result (photo 3 A-B). Rashes and congestive spots were eliminated, and the formation of post-acne scars was prevented. This has proven that plasma therapy is an effective method for the prevention and treatment of patients with acne. <img alt="" src="https://pro.bhub.com.ua/cosmetology/upload/files/01/top/cosmetology%20%283%29/arch/cosm/%D0%A1%D0%BD%D0%B8%D0%BC%D0%BE%D0%BA%20%D1%8D%D0%BA%D1%80%D0%B0%D0%BD%D0%B0%202021-03-22%20%D0%B2%2017.46.52.png" style="width: 703px; height: 386px;" /><img alt="" src="https://pro.bhub.com.ua/cosmetology/upload/files/01/top/cosmetology%20%283%29/arch/cosm/%D0%A1%D0%BD%D0%B8%D0%BC%D0%BE%D0%BA%20%D1%8D%D0%BA%D1%80%D0%B0%D0%BD%D0%B0%202021-03-22%20%D0%B2%2017.45.44.png" style="width: 705px; height: 386px;" /><img alt="" src="https://pro.bhub.com.ua/cosmetology/upload/files/01/top/cosmetology%20%283%29/arch/cosm/%D0%A1%D0%BD%D0%B8%D0%BC%D0%BE%D0%BA%20%D1%8D%D0%BA%D1%80%D0%B0%D0%BD%D0%B0%202021-03-22%20%D0%B2%2017.46.06.png" style="width: 703px; height: 425px;" /> Literature: Dmitry Shavalyuk, general practitioner, cosmetologist (Ukraine) <a href="https://afisha.bhub.com.ua/event/magazines/lne/les-nouvelles-esthetiques-2021-1" target="_blank">Les Nouvelles Esthétiques Ukraine 1/2021</a><div></div>

The use of plasma therapy in patients with acne