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The article was translated into English using automatic translation. The editors are working on its improvement.

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Skin quality

Science

Care methods

Cosmetics

The history of great discoveries often begins with accidents. This is exactly what happened to the Klotho protein back in 1997, when Japanese researchers led by Makoto Kuro-o discovered the Klotho gene.

While studying transgenic mice expressing a sodium-proton exchanger, scientists accidentally damaged the locus of a nearby gene, and the mice showed a striking phenomenon reminiscent of human aging. This phenomenon was noted:

<ul>
	<li>growth</li>
	<li>retardation;</li>
	<li>hypogonadism;</li>
	<li>atrophy of the skin, thymus;</li>
	<li>calcification of blood vessels and soft tissues;</li>
	<li>osteoporosis;</li>
	<li>pulmonary emphysema.</li>
</ul>

In contrast, overexpression of Klotho in mice led to increased lifespan. Therefore, the discovered gene was named after one of the goddesses of fate, the goddess Klotho, who spins the thread of life.

Full version of the access article <a href="https://pro.bhub.com.ua/cosmetology/stimulyuvannya-metabolizmu-shkiri-mojlivosti-transmembrannogo-proteinu">in Ukrainian</a>

Stimulation of skin metabolism: possibilities of transmembrane protein