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Science

Anaphylactic shock is a severe manifestation of an immediate allergic reaction. It is characterized by a rapidly increasing drop in vascular tone (a drop in blood pressure, collapse), an increase in the permeability of vessels with the release of the liquid part of the blood into the tissues (at the same time, a decrease in the volume of circulating blood, thickening of the blood), the development of bronchospasm and spasm of the striated muscles of internal organs.

It develops 3-30 minutes after the introduction of the drug, while the route of administration is not important. Anaphylactic shock can occur after taking drugs internally, in the form of inhalation, intradermal (in particular, during allergy testing), subcutaneous, intramuscular, and intravenous administration.

When an allergen is administered parenterally and especially intravenously, it develops more often and earlier (sometimes &quot;at the tip of a needle&quot; - rapid development of anaphylactic shock). After rectal, oral, external use of the drug, this condition is observed after 1-3 hours. The sooner anaphylactic shock develops after contact with an allergen, the more severe its course and the more likely death occurs.

Full version of the access article <a href="https://pro.bhub.com.ua/cosmetology/reakcii-na-likarski-preparati-anafilaktichniy-shok">in Ukrainian</a>

Reactions to drugs: anaphylactic shock