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*The article was translated into English using automatic translation. The editors are working on its improvement.

Wrinkles are folds of the skin that appear as a result of loss of skin elasticity and firmness, excessive activity of facial muscles, exposure to ultraviolet radiation and other reasons. The elasticity of the skin is given by the collagen fibers contained in the dermis, and the elasticity is provided by the hyaluronic acid (HA) molecules located between them.